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Middlebrook ADC 增菌液
基本售價：1800.00元
Middlebrook ADC 增菌液使用說明書 貨號：LA0270 規格：20ml×20 支/箱 保存：有效期 180 天，A 組分于 2-8℃保存，B 組分于-20℃保存。 產品用途：(Middlebrook 7H9 肉湯基礎)添加劑。 A 組分 1 支及 B 組分 2 支同時用于 180ml 上述培養基基礎中。 產品組份：（g/L） A 組分：氯化鈉 8.5g；葡萄糖 20g；牛血清白蛋白 V 50g。 B 組分：過氧化氫酶 0.03g。 使用方法：從冷凍環境取出后，于 35℃水浴約 10 分鐘使融化；培養基滅菌后，冷卻至 50-55℃， 無菌環境下，無菌操作加入培養基中，輕輕搖勻。 產品性能指標： 1、理化：無色、澄清、透明、無雜質 2、無菌性檢測：無菌操作，加入雙倍無菌液體硫乙醇酸鹽培養基中，培養，無菌生長。 注意事項： 1、開封后未使用完請及時密封并至于冷藏柜中保存，并避免染菌。 2、用于實驗室微生物檢測。
α-酮戊二酸（α-KG）熒光法測試盒
基本售價：3280.00元
α-Ketoglutarate (α-KG) Fluorometric Assay Kit中文名稱:α-酮戊二酸（α-KG）熒光法測試盒檢測儀器及波長:熒光酶標儀(激發波長535 nm，發射波長587 nm)樣本類型: 血清;血漿;尿液;動物組織和細胞 檢測原理α-酮戊二酸與丙氨酸在系列酶的作用下生成能與熒光探針結合的產物，通過測定熒光值大小判斷樣本中α-酮戊二酸含量。關鍵信息指標簡稱α-KG樣本類型血清;血漿;尿液;動物組織和細胞靈敏度0.60 μmol/L檢測范圍0.60-100 μmol/L精密度批間差：4% | 批內差：2%檢測儀器及波長熒光酶標儀(激發波長535 nm，發射波長587 nm)特殊儀器熒光酶標儀(激發波長535 nm，發射波長587 nm) ，恒溫箱(37°C)，低溫離心機自備試劑生理鹽水(0.9% NaCl)保存條件-20℃有效期6個月
Caspase 9活性檢測試劑盒(分光光度法)
基本售價：500.00元
Caspase 9 Activity Colorimetric Assay Kit文獻(3) 中文名稱:Caspase 9活性檢測試劑盒(分光光度法)貨號:E-CK-A313檢測原理 Caspase(Cysteine-requiring Aspartate Protease)是在細胞凋亡過程中起重要作用的蛋白酶家族。Caspase 9也稱ICE-LAP6或Mch6，Caspase 9被認為是細胞凋亡信號轉導過程中上游的一個Caspase。線粒體釋放細胞色素c后，Caspase 9可以和細胞色素c以及Apaf1形成復合物，同時被激活。激活的Caspase 9可以激活細胞凋亡的最關鍵酶Caspase3，從而促進后續的細胞凋亡信號。Caspase 9的激活可通過磷酸化進行調控。Caspase 9 在正常狀態下以酶原的形式存在于胞漿中，沒有活性；但在細胞發生凋亡階段，它被激活，最終導致細胞凋亡。 Caspase 9分光光度法檢測試劑盒的原理是將Caspase 9序列特異性的多肽（Ac-LEHD-pNA (acetyl-Asp-Glu-Val-Asp p-nitroanilide）偶聯至黃色發光基團pNA (p-nitroaniline)。當該底物被Caspase 9剪切后，黃色發光基團pNA游離出來，可通過酶標儀或分光光度計（λ=405nm 或400nm）測定其吸光值，通過測定吸光度來檢測Caspase 9的活性?；拘畔?應用類型細胞凋亡-Caspase檢測類型定性分析檢測方法比色法樣本類型細胞，組織檢測時間4-6 hours檢測儀器分光光度計自備試劑PBS(E-BC-R187)，Bradford蛋白測定試劑盒(E-BC-K168-S或E-BC-K168-M)保存溫度-20°C, shading light運輸條件冰袋保質期12 months
Caspase 8活性檢測試劑盒(分光光度法)
基本售價：500.00元
Caspase 8 Activity Colorimetric Assay Kit文獻(2) 中文名稱:Caspase 8活性檢測試劑盒(分光光度法)貨號:E-CK-A312檢測原理 Caspase (Cysteine-requiring Aspartate Protease)是在細胞凋亡過程中起重要作用的蛋白酶家族。Caspase 8也稱FLICE、MACH或Mch5，Caspase 8被認為是細胞凋亡信號轉導過程中上游的一個Caspase，在Fas-receptor和TNFR-1介導的細胞凋亡過程中Caspase 8被激活，形成一個由p18和p10組成的二聚體，進一步激活下游的Caspase 4，Caspase 6，Caspase 9和Caspase 10。Caspase 8在正常狀態下以酶原的形式存在于胞漿中，無活性；在細胞發生凋亡階段，Caspase 8被激活，參與細胞凋亡過程。 Caspase 8分光光度法檢測試劑盒的原理是將Caspase 8序列特異性的多肽（Ac-IETD-pNA (acetyl-Ile-Glu-Thr-Asp p-nitroanilide）偶聯至黃色集團pNA (p-nitroaniline)。當該底物被Caspase 8剪切后，黃色基團pNA游離出來，可通過酶標儀或分光光度計（λ=405nm 或400nm）測定其吸光值，通過測定吸光度來檢測Caspase 8的活性。基本信息 應用類型細胞凋亡-Caspase檢測類型定性分析檢測方法比色法樣本類型細胞，組織檢測時間4-6 hours檢測儀器分光光度計自備試劑PBS(E-BC-R187)，Bradford蛋白測定試劑盒(E-BC-K168-S或E-BC-K168-M)保存溫度-20°C, shading light運輸條件冰袋保質期12 months
Caspase 3/7活性檢測試劑盒(分光光度法)
基本售價：500.00元
Caspase 3/7 Activity Assay Kit(Colorimetric Method)中文名稱:Caspase 3/7活性檢測試劑盒(分光光度法)貨號:E-CK-A383檢測原理 Caspase 3也稱CPP32、Yama或apopain，屬于Caspase家族的CED-3亞家族(CED-3 subfamily)，是細胞凋亡過程中的一個關鍵酶，也是哺乳動物細胞中研究最多的一個caspase。Caspase 3在正常狀態下以酶原的形式存在于胞漿中，沒有活性；在細胞發生凋亡階段，Caspase 3被激活，活化的caspase 3由兩個大亞基和兩個小亞基組成，裂解相應的胞漿胞核底物，最終導致細胞凋亡。本caspase 3/7活性檢測試劑盒是基于caspase 3/7可以催化底物Ac-DEVD-pNA產生黃色的pNA(p-nitroaniline)，pNA在405nm附近有強吸收，從而可以通過測定吸光度來檢測caspase 3/7的活性。基本信息 應用類型細胞凋亡-Caspase檢測類型定性分析或定量分析檢測方法比色法樣本類型細胞，組織檢測時間4-6 hours檢測儀器分光光度計自備試劑PBS(E-BC-R187)，Bradford蛋白測定試劑盒(E-BC-K168-S或E-BC-K168-M)保存溫度-20℃，避光運輸條件冰袋保質期6 months
Caspase 6活性檢測試劑盒(分光光度法)
基本售價：500.00元
Caspase 6 Activity Assay Kit(Colorimetric Method)中文名稱:Caspase 6活性檢測試劑盒(分光光度法)貨號:E-CK-A386檢測原理 Caspase 6也稱Mch-2，最初從人的Jurkat細胞中被發現。Caspase 6的前體被granzyme B剪切后可以形成活化的 caspase 6二聚體，而活化的caspase 6被發現可以誘導細胞凋亡。Caspase 6可以剪切PARP和keratin-18，也可以剪切細胞核核被膜上的關鍵組成蛋白Lamin A。Caspase家族中僅caspase 6可以剪切Lamin A。本caspase 6活性檢測試劑盒是基于caspase 6可以催化底物Ac-VEID-pNA產生黃色的pNA(p-nitroaniline)，pNA在405nm附近有強吸收，從而可以通過測定吸光度來檢測caspase 6的活性?；拘畔?應用類型細胞凋亡-Caspase檢測類型定性分析或定量分析檢測方法比色法樣本類型細胞，組織檢測時間4-6 hours檢測儀器分光光度計自備試劑PBS(E-BC-R187)，Bradford蛋白測定試劑盒(E-BC-K168-S或E-BC-K168-M)保存溫度-20℃，避光運輸條件冰袋保質期6 months
Caspase 2活性檢測試劑盒(分光光度法)
基本售價：500.00元
Caspase 2 Activity Assay Kit(Colorimetric Method)中文名稱:Caspase 2活性檢測試劑盒(分光光度法)貨號:E-CK-A382檢測原理 Caspase 2也稱Ich-1 (ICE and CED-3 homolog 1)或Nedd-2，在細胞凋亡的信號轉導過程中可以被激活。Caspase 2 mRNA可以被剪切成兩種不同長短的形式。Caspase 2全長的mRNA產物可以促進凋亡，而短的mRNA的蛋白產物則可以抑制細胞凋亡。在體外，Caspase 2可以被caspase 1、caspase 3和granzyme B激活。本caspase 2活性檢測試劑盒是基于caspase 2可以催化底物Ac-VDQQD-pNA產生黃色的pNA(p-nitroaniline)，pNA在405nm附近有強吸收，從而可以通過測定吸光度來檢測caspase 2的活性?；拘畔?應用類型細胞凋亡-Caspase檢測類型定性分析或定量分析檢測方法比色法樣本類型細胞，組織檢測時間4-6 hours檢測儀器分光光度計自備試劑PBS(E-BC-R187)，Bradford蛋白測定試劑盒(E-BC-K168-S或E-BC-K168-M)保存溫度-20℃，避光運輸條件冰袋保質期6 months
Caspase 1活性檢測試劑盒(分光光度法)
基本售價：500.00元
Caspase 1 Activity Assay Kit(Colorimetric Method)中文名稱:Caspase 1活性檢測試劑盒(分光光度法)貨號:E-CK-A381檢測原理 Caspase 1也稱interkeukin 1β conberting enzyme (ICE)，是caspase家族中唯一可以剪切IL-1β前體蛋白或IL-18前體產生相應成熟的細胞因子的caspase。Caspase 11可以剪切45 kD的caspase 1前體蛋白，產生20 kD和10 kD的片段，這兩個片段可以形成異源二聚體 (heterodimer)，并進一步由兩個異源二聚體形成四聚體。Caspase 1可以通過剪切Bcl-XL來調節細胞凋亡，并通過剪切細胞因子的前體來調節相關的免疫反應，也可以通過水解Gastermin D (GSDMD)來調節細胞焦亡。本caspase 1活性檢測試劑盒是基于caspase 1可以催化底物Ac-YVAD-pNA產生黃色的pNA (p-nitroaniline)，pNA在405 nm附近有強吸收，從而可以通過測定吸光度來檢測caspase 1的活性?；拘畔?應用類型細胞凋亡-Caspase檢測類型定性分析或定量分析檢測方法比色法樣本類型細胞，組織檢測時間4-6 hours檢測儀器分光光度計自備試劑PBS(E-BC-R187)，Bradford蛋白測定試劑盒(E-BC-K168-S或E-BC-K168-M)保存溫度-20℃，避光運輸條件冰袋保質期6 months
人二胺氧化酶(DAO)酶聯免疫吸附測定試劑盒
基本售價：3200.00元
產品貨號:E-EL-H1241c 中文名:人二胺氧化酶(DAO)酶聯免疫吸附測定試劑盒別稱:AOC1, ABP1, Amiloride Binding Protein 1, Amine Oxidase(Copper-Containing)用途 該試劑盒用于體外定量檢測Human 血清，血漿或其他生物體液中DAO濃度檢測原理 本試劑盒采用雙抗體夾心ELISA法。用抗人DAO抗體包被于酶標板上，實驗時樣品或標準品中的人DAO會與包被抗體結合，游離的成分被洗去。依次加入生物素化的抗人DAO抗體和辣根過氧化物酶標記的親和素?？谷薉AO抗體與結合在包被抗體上的人DAO結合、生物素與親和素特異性結合而形成免疫復合物，游離的成分被洗去。加入顯色底物(TMB)，TMB在辣根過氧化物酶的催化下呈現藍色，加終止液后變成黃色。用酶標儀在450nm波長處測OD值，DAO濃度與OD450值之間呈正比，通過繪制標準曲線計算出樣品中DAO的濃度。反應類型 夾心法規格 96T反應時間 3.5h反應性 Human檢測方法 Colormetric檢測范圍 3.13—200 ng/mL靈敏度 1.88 ng/mL樣本體積 100μL樣本類型 血清，血漿或其他生物體液特異性 可檢測樣本中的人DAO，且與其它相關蛋白無明顯交叉反應。重復性 板內，板間變異系數均<10%。典型數據 由于實驗操作條件的不同（如操作者、移液技術、洗板技術和穩定條件等），標準曲線的OD值會有所差異。以下數據和曲線僅供參考，實驗者需根據自己的實驗建立標準曲線。(ng/mL) O.D Average Corrected 2002.4072.4412.4242.3351001.5471.6051.5761.487500.9180.8960.9070.817250.4660.4840.4750.38612.50.280.2780.2790.196.250.1980.1680.1830.0943.130.1290.1470.1380.04900.0870.090.089--精密度板內精密度:低濃度樣本,中濃度樣本和高濃度樣本分別在1塊板子上檢測20次。板間精密度:低濃度樣本,中濃度樣本和高濃度樣本分別在3塊板子上檢測20次。Intra-assay Precision Inter-assay Precision Sample 123123n 202020202020Mean(ng/mL) 10.7428.2690.3810.9527.5989.37Standarddeviation 0.681.293.070.641.433.93C V (%) 6.334.563.405.845.184.40回收率 分別往5個不同樣本中添加已知濃度的目標蛋白，做回收實驗，得出回收率范圍和平均回收率。Sample Type Range (%) Average Recovery (%) Serum (n=8) 92-10698EDTA plasma (n=8) 85-10092Cell culture media (n=8) 89-10295線性 分別往5個樣本中添加已知濃度的目標蛋白，做回收實驗，得出回收率范圍及平均回收率。將5個樣本分別稀釋2倍，4倍，8倍，16倍做回收實驗，得出回收率范圍及平均回收率。Serum (n=5) EDTA plasma (n=5) Cell culture media (n=5) 1:2Range (%)94-10789-10195-109Average (%)99941011:4Range (%)87-10385-10088-103Average (%)9491951:8Range (%)88-10586-10088-104Average (%)9692951:16Range (%)89-10182-9682-96Average (%)948888試劑盒組成及保存 未拆封的試劑盒可在2-8℃保存一周；如果一周以后才使用試劑盒，請拆開試劑盒按照下表中的條件分別保存各組分。中文名稱 英文名稱 規格 保存條件 ELISA酶標板(可拆卸)Micro ELISA Plate(Dismountable)8 孔×12 條-20℃，可存放6個月凍干標準品Reference Standard2 支濃縮生物素化抗體(100×)Concentrated Biotinylated Detection Ab1支 120 μL濃縮HRP酶結合物(100×)Concentrated HRP Conjugate1支 120 μL-20℃(避光)，可存放6個月標準品&樣品稀釋液Reference Standard & Sample Diluent1瓶 20 mL2-8℃.可存放6個月生物素化抗體稀釋液Biotinylated Detection Ab Diluent1瓶 14 mL酶結合物稀釋液HRP Conjugate Diluent1瓶 14 mL濃縮洗滌液(25×)Concentrated Wash Buffer (25×)1瓶 30 mL底物溶液(TMB)Substrate Reagent1瓶 10 mL2-8℃(避光)反應終止液Stop Solution1瓶 10 mL2-8℃封板覆膜Plate Sealer5 張產品說明書Product Description1 份質檢報告Certificate of Analysis1 份說明：所有試劑瓶蓋須旋緊以防止蒸發和微生物的污染。試劑體積以實際發貨版說明書為準。相關試劑在分裝時會比標簽上標明的體積稍多一些，請在使用時量取而非直接倒出。試驗所需自備物品 1. 酶標儀(450nm波長濾光片)2. 高精度移液器，EP管及一次性吸頭：0.5-10 μL, 2-20 μL, 20-200 μL, 200-1000 μL3. 37℃恒溫箱，雙蒸水或去離子水4. 吸水紙
即用型正常山羊血清
基本售價：40.00元
產品貨號:E-IR-R110 中文名:即用型正常山羊血清別稱:山羊血清,Normal Goat,封閉液，IHC封閉液，IF封閉液產品簡介 本品為正常山羊血清加入穩定劑，作為封閉液可效減少IHC/IF實驗的非特異染色從而降低背景。 產品組成 產品編號 產品名稱 5 mL 10 mL 50 mL Storage E-IR-R110 Normal Goat Blocking Buffer (Ready-to-Use) 5 mL 10 mL 50 mL 2~8°C 產品使用說明 本產品為即用型山羊血清，可直接使用。 作為對照IgG使用時，用量和其它IgG的用量應相同。對照IgG用量過多可能會導致背景過高。 作為免疫組化封閉液，請直接滴加到組織切片上進行封閉。 保存條件 2~8°C保存，有效期12個月。 注意事項 1.本產品僅限于專業人員的科學研究用，不得用于臨床診斷或治療，不得用于食品或藥品，不得存放于普通住宅內。2.為了您的安全和健康，請穿實驗服并戴一次性手套操作。
Recombinant Human FGF-10(Cat. No.:CR11)
基本售價：14400.00元
Recombinant Human FGF-10(Cat. No.:CR11) 該產品共有2篇文獻引用 產品描述Recombinant Human Fibroblast Growth Factor 10 is produced by our E.coli expression system and the target gene encoding Gln38-Ser208 is expressed.蛋白編號O15520 產品別稱Fibroblast growth factor 10;FGF-10;Keratinocyte growth factor 2;FGF10;KGF-2;KGF2分子量19.5 KDa表觀分子量19-22 KDa, reducing conditions劑型描述Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, pH 8.0.內毒素Less than 0.001 ng/μg (0.01 EU/μg) as determined by LAL test.純度-SDS-PAGEGreater than 95% as determined by reducing SDS-PAGE. 純度-SEC-HPLCGreater than 95% as determined by SEC-HPLC. (Regularly tested) 生物活性-Cell Based AssayMouse Gastric organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) , R-spondin 1 (Cat#CX83) and FGF-10 (Cat#CR11). The organoids showed good morphology. Mouse bile duct organoids were cultured with EGF (Cat#C029) , R-spondin 1 (Cat#CX83) ,FGF-10 (Cat#CR11) and HGF (Cat#CJ72). The organoids showed good morphology. 復溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存條件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.運輸條件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.產品背景Fibroblast growth factor 10 (FGF-10, KGF-2), is a member of the fibroblast growth factor (FGF) family that includes FGF-3, -7, and -22. KGF-2 is secreted by mesenchymal cells and associates with extracellular FGF-BP. It preferentially binds and activates epithelial cell FGFR2 and interacts more weakly with FGFR1. It plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. It exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 is required for normal branching morphogenesis. Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG). ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.僅供科研或生產使用，不可直接應用于人體。
Recombinant Human RSPO1 (C-6His)(Cat. No.:CX83)
基本售價：17600.00元
Recombinant Human RSPO1 (C-6His)(Cat. No.:CX83) 該產品共有5篇文獻引用 產品描述Recombinant Human R-spondin-1 is produced by our Mammalian expression system and the target gene encoding Ser21-Ala263 is expressed with a 6His tag at the C-terminus.蛋白編號Q2MKA7 產品別稱RSPO1; R-spondin1; RP11-566C13.1; CRISTIN3; FLJ40906; RSPO Rspo1; R-spondin; Rspondin; RP23-325M14.2; Roof plate-specific spondin-1分子量27.8 KDa表觀分子量40 KDa, reducing conditions劑型描述Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.內毒素Less than 0.01 EU/μg as determined by LAL test.純度-SDS-PAGEGreater than 95% as determined by reducing SDS-PAGE. 生物活性-Cell Based AssayMeasured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 4.06 ng/ml. Mouse intestinal organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) and R-spondin 1 (Cat#CX83). After five days of culture, the organoids showed good morphology and germination rate. Mouse Colon organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) , and R-spondin 1 (Cat#CX83). The organoids showed good morphology. Mouse Gastric organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) , R-spondin 1 (Cat#CX83) and FGF-10 (Cat#CR11). The organoids showed good morphology. Mouse bile duct organoids were cultured with EGF (Cat#C029) , R-spondin 1 (Cat#CX83) ,FGF-10 (Cat#CR11) and HGF (Cat#CJ72). The organoids showed good morphology. Human intestinal organoids (ipsc source) were cultured with Activin A(Cat#C687) , BMP-4(sample) , EGF (Cat#C029) , Wnt3a (Cat#C22R), Noggin (Cat#C028), R-spondin 1 (Cat#CX83) and FGF-4 (Cat#CR08) . The organoids showed good morphology. Human endometrial epithelial organoids were cultured with EGF (Cat#CH28) and R-spondin 1 (Cat#CX83). The organoids showed good morphology. Data were kindly provided by Novoprotein's customer. Thanks for her contribution. 復溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存條件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.運輸條件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.產品背景RSPO1 is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. RSPO1 is required for the early development of gonads, regardless of sex. It has been found in mice only eleven days after fertilization. To induce cell proliferation, it acts synergistically with WNT4. They help stabilize β catenin, which activates downstream targets. RSPO1 is necessary in female sex development. It augments the WNT/β catenin pathway to oppose male sex development. In critical gonadal stages, between six and nine weeks after fertilization, the ovaries upregulate it while the testes downregulate it. RSPO1 can potentially aid in the treatment of mucositis, which is characterized by inflammation of the oral cavity. This unfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and neck tumors.僅供科研或生產使用，不可直接應用于人體。
Recombinant Human KGF(Cat. No.:CH73)
基本售價：19200.00元
Recombinant Human KGF(Cat. No.:CH73) 該產品共有1篇文獻引用 產品描述Recombinant Human Fibroblast Growth Factor 7/Keratinocyte Growth Factor is produced by our E.coli expression system and the target gene encoding Cys32-Thr194 is expressed.蛋白編號P21781 產品別稱Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF分子量18.9 KDa表觀分子量17 KDa, reducing conditions劑型描述Lyophilized from a 0.2 μm filtered solution of 20mM Tris，1mM EDTA，5% Trehalose, 0.02% Tween 80, pH 8.0.內毒素Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.純度-SDS-PAGEGreater than 95% as determined by reducing SDS-PAGE. (QC verified) 純度-SEC-HPLCGreater than 95% as determined by SEC-HPLC. (Regularly tested) 復溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存條件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.運輸條件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.產品背景Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.僅供科研或生產使用，不可直接應用于人體。
Recombinant Human PECAM-1 (C-6His)(Cat. No.:CS74)
基本售價：400.00元
Recombinant Human PECAM-1 (C-6His)(Cat. No.:CS74) 產品描述Recombinant Human Platelet Endothelial Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Gln28-Lys601 is expressed with a 6His tag at the C-terminus.蛋白編號AAH51822.1 產品別稱Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1分子量65.3 KDa表觀分子量75-110 KDa, reducing conditions劑型描述Lyophilized from a 0.2 μm filtered solution of PBS, 1mM EDTA, pH 7.4.內毒素 Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.復溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存條件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.運輸條件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.產品背景Platelet Endothelial Cell Adhesion Molecule (PECAM1, CD31), is a heavily glycosylated transmembrane protein belonging to the immunoglobulin (Ig) superfamily of cell adhesion molecules. CD31 is composed of an extracellular domain (ECD) of 574 amino acids (aa) containing six Ig-like domains, a transmembrane domain, and a 118 aa cytoplasmic domain. CD31 is highly expressed on endothelial cells and at a lower level on platelets, granulocytes, macrophages, dendritic cells, T and B cells, and natural killer (NK) cells. It is involved in cell adhesion and is required for transepithelial migration of leukocytes (TEM). CD31 acts as a homophilic receptor through its extracellular domain and is involved in downstream signaling via its cytoplasmic domain. This domain contains highly conserved ITIM motifs which, once tyrosine phosphorylated, recruit and activate the signaling molecules Src and SHP2. The resulting inhibition of TCR signaling increases the activation threshold of T cells, thus reinforcing peripheral tolerance and preventing development of autoimmunity. CD31 additionally regulates immune responses by acting as a key inhibitory receptor in dendritic cell development. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells.僅供科研或生產使用，不可直接應用于人體。
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